Products for Research Use Only
RegisterLogin

MRK003

CAT: 0013-GTR19210958-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19210958-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MRK003 is a γ-secretase inhibitor demonstrating potent preclinical activity against multiple myeloma and non-Hodgkin's lymphoma cell lines and patient samples. It induces caspase-dependent apoptosis, modulates key proteins like Notch, c-Myc, and Bcl-2 family members, and shows crosstalk with the PI3K/Akt pathway, supporting its use in oncology research for in vitro mechanism of action studies.
CAS Number
623165-93-5
Field of Research
Cell Biology, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
C (C (F) (F) F) N1C[C@@]2 ([C@]3 (CC=4C (C[C@@]2 (CC3) [H]) =CC=C (/C=C/CN5CCC (C (F) (F) F) CC5) C4) [H]) NS1 (=O) =O
Molecular Formula
C25H31F6N3O2S
Molecular Weight
551.59
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
MBS5811534MRK003

Popular Products