Products for Research Use Only

L2-b

CAT: 0013-GTR19210775-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210775-01Size:25 mg
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Description
L2-b is a bifunctional small molecule that targets amyloid-beta (Aβ) pathology by chelation of copper and zinc. It inhibits metal-induced Aβ aggregation, disrupts pre-formed aggregates in AD brain homogenates, and reduces associated reactive oxygen species in cellular models, thereby improving neuronal cell viability. This makes it a valuable research tool for studying metallobiology in Alzheimer's disease.
CAS Number
52688-60-5
Smiles
N (CC1=CC=CC=N1) C2=CC=C (N (C) C) C=C2
Molecular Formula
C14H17N3
Molecular Weight
227.3
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N1,N1-Dimethyl-N4-[(pyridin-2-yl)methyl]benzene-1,4-diamine
CAS Number52688-60-5
PubChem CID39247144
IUPAC Name4-N,4-N-dimethyl-1-N-(pyridin-2-ylmethyl)benzene-1,4-diamine
Molecular FormulaC14H17N3
Molecular Weight227.30
XLogP2.5
Topological Polar Surface Area28.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count17
Formal Charge0
Complexity210
SMILES
CN(C)C1=CC=C(C=C1)NCC2=CC=CC=N2
InChI
InChI=1S/C14H17N3/c1-17(2)14-8-6-12(7-9-14)16-11-13-5-3-4-10-15-13/h3-10,16H,11H2,1-2H3
InChIKey
RIKLBFYMQFBFJF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N1,N1-Dimethyl-N4-[(pyridin-2-yl)methyl]benzene-1,4-diamine
CAS: 52688-60-5
CID: 39247144
Formula: C14H17N3
MW: 227.30
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight227.30
XLogP32.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass227.142247555
Monoisotopic Mass227.142247555
Topological Polar Surface Area28.2 Ų
Heavy Atom Count17
Formal Charge0
Complexity210
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes