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Hexokinase (ScHEX1)

CAT: 0013-GTR19220105-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19220105-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The glycolytic enzyme hexokinase (ScHEX1) dissociates from mitochondria upon inhibition by N-acetylglucosamine, a process known to trigger NLRP3 inflammasome activation. This small molecule is a valuable research tool for studying immunometabolism, inflammasome regulation, and related pathways in both cellular and animal models of inflammatory disease.
CAS Number
9001-51-8
Field of Research
Metabolism Research, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

recombinant Hexokinase

See also: Hexokinase (annotation moved to).

CAS Number9001-51-8
PubChem CID176259338
IUPAC Name5-[(2S)-2-(2-chlorophenyl)pyrrolidin-1-yl]-N-[(E,2R)-4-methylsulfonylbut-3-en-2-yl]pyrimidine-2-carboxamide
Molecular FormulaC20H23ClN4O3S
Molecular Weight434.9
XLogP2.5
Topological Polar Surface Area101
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count29
Formal Charge0
Complexity688
SMILES
C[C@H](/C=C/S(=O)(=O)C)NC(=O)C1=NC=C(C=N1)N2CCC[C@H]2C3=CC=CC=C3Cl
InChI
InChI=1S/C20H23ClN4O3S/c1-14(9-11-29(2,27)28)24-20(26)19-22-12-15(13-23-19)25-10-5-8-18(25)16-6-3-4-7-17(16)21/h3-4,6-7,9,11-14,18H,5,8,10H2,1-2H3,(H,24,26)/b11-9+/t14-,18+/m1/s1
InChIKey
MPGKRMWXKMIVII-OCJFRMIVSA-N
Chemical Structure
2D Structure
2D structure of recombinant Hexokinase
CAS: 9001-51-8
CID: 176259338
Formula: C20H23ClN4O3S
MW: 434.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight434.9
XLogP32.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass434.1179395
Monoisotopic Mass434.1179395
Topological Polar Surface Area101 Ų
Heavy Atom Count29
Formal Charge0
Complexity688
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS5818018Hexokinase (ScHEX1)
532315-01Hexokinase
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H2040-51MHexokinase 4 (Glucokinase, Hexokinase Type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D, GCK)
127887HK3 (Hexokinase-3, Hexokinase Type III, HK III, Hexokinase 3)
E2200569Hexokinase-2/Hexokinase II Mouse mAb
10R-1056Hexokinase antibody
318744-01Hexokinase-1
AP84269-01Hexokinase-3
AP83881Hexokinase-2

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