Products for Research Use Only
RegisterLogin

Celiptium

CAT: 0013-GTR19210874-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19210874-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Elliptinium acetate (NSC 264137) is a DNA-intercalating agent that covalently binds nucleic acids, demonstrating high cytotoxicity against L1210 leukemia cells in vitro. Its research applications include studies in metastatic breast cancer, supported by investigations into its antitumor activity in both cellular and animal models.
CAS Number
58337-35-2
Field of Research
Cell Biology
Smiles
O=C ([O-]) C.OC1=CC=C2NC=3C (C2=C1) =C (C=4C=[N+] (C=CC4C3C) C) C
Molecular Formula
C20H20N2O3
Molecular Weight
336.38
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Elliptinium Acetate

Elliptinium Acetate is acetate salt of elliptinium, a derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria vitensis, a plant with anti-cancer properties. As a topoisomerase II inhibitor and intercalating agent, elliptinium stabilizes the cleavable complex of topoisomerase II and induces DNA breakages, thereby inhibiting DNA replication and RNA and protein synthesis.

CAS Number58337-35-2
PubChem CID42722
IUPAC Name2,5,11-trimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol acetate
Molecular FormulaC20H20N2O3
Molecular Weight336.4
Topological Polar Surface Area80
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Heavy Atom Count25
Formal Charge0
Complexity426
SMILES
CC1=C2C=C[N+](=CC2=C(C3=C1NC4=C3C=C(C=C4)O)C)C.CC(=O)[O-]
InChI
InChI=1S/C18H16N2O.C2H4O2/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18;1-2(3)4/h4-9,21H,1-3H3;1H3,(H,3,4)
InChIKey
BOMZMNZEXMAQQW-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Elliptinium Acetate
CAS: 58337-35-2
CID: 42722
Formula: C20H20N2O3
MW: 336.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight336.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count0
Exact Mass336.14739250
Monoisotopic Mass336.14739250
Topological Polar Surface Area80 Ų
Heavy Atom Count25
Formal Charge0
Complexity426
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Popular Products