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DX314

CAT: 0013-GTR19213392Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19213392Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DX314 is a potent, specific CYP26B1 inhibitor with IC50 of 108 nM, >15-fold selectivity over CYP26A1.DX314 potentiates all-trans-RA (atRA) gene expression effects in healthy and diseased reconstructed human epidermis (RHE) .DX314 potentiates the effects of atRA on the expression and localization of keratin 10 (KRT10), protects barrier function in RHE.DX314 reduces comedonal number, induces epidermal thickening, and increases comedonal profile, while having no effect on transepidermal water loss (TEWL) in treated rhino mice.
CAS Number
1662711-07-0
Purity
>98%
Molecular Formula
C25H29NO3
Molecular Weight
391.511
Notes
For research use only.

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