Products for Research Use Only

SR1903 TFA

CAT: 0013-GTR19210343-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210343-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SR-1903 is a dual modulator acting as an inverse agonist of RORγ and an agonist of LXR, with additional binding to PPARγ without activation. It suppresses LPS-induced inflammatory pathways, including TREM-1, IL-6, and IL-33, while promoting lipid metabolism genes like ABCG1. This compound has demonstrated efficacy in preclinical models of autoimmune arthritis and metabolic disorders, reducing inflammation, cholesterol, and body weight.
CAS Number
2351884-03-0
Field of Research
Immunology & Inflammation
Smiles
C (C (O) =O) (F) (F) F.CC1=C (C2=CC=C (C (C (F) (F) F) (C (F) (F) F) O) C=C2) C=CC (CN3CCN (CC=4C=CN=CC4) CC3) =C1
Molecular Formula
C29H28F9N3O3
Molecular Weight
637.54
Storage Conditions
-20°C
Notes
For research use only.