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MS-177

CAT: 0013-GTR19210244-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210244-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MS-177 is a PROTAC-based EZH2 degrader that inhibits leukemia and multiple myeloma cell growth by inducing apoptosis and cell cycle arrest. It degrades both classical and non-classical EZH2 complexes, modulating pathways like WNT/β-catenin and activating immune-responsive genes, applicable for in vitro and in vivo cancer research.
CAS Number
2225938-86-1
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
O=C (NCC=1C (=O) NC (=CC1C) C) C2=CC (=CC3=C2C=NN3C (C) C) C=4C=NC (=CC4) N5CCN (CCNC (=O) CCOCCNC6=CC=CC=7C (=O) N (C (=O) C67) C8C (=O) NC (=O) CC8) CC5
Molecular Formula
C48H55N11O8
Molecular Weight
914.02
Storage Conditions
-20°C
Notes
For research use only.

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