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NSC109131

CAT: 0013-GTR19210116-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210116-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC109131 is a potent and selective small molecule inhibitor of the DNA repair enzyme tyrosyl-DNA phosphodiesterase 1 (TDP1) . It is a valuable research tool for studying TDP1's role in cellular resistance to topoisomerase I poisons, such as camptothecin, in both in vitro and in vivo cancer research models.
CAS Number
21170-27-4
Smiles
C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) C (CC3) =CC (=O) CC4) (CC1) [H]) [H]) (CC[C@@H]2C (CN5C=6C (N=C5) =C (SC) N=CN6) =O) [H]
Molecular Formula
C27H34N4O2S
Molecular Weight
478.65
Storage Conditions
-20°C
Notes
For research use only.

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