Products for Research Use Only
RegisterLogin

MFH290

CAT: 0013-GTR19210074-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19210074-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MFH290 is a selective covalent inhibitor targeting CDK12/13 via Cys-1039. It suppresses Pol II CTD Ser2 phosphorylation and DNA damage repair gene expression, synergizing with PARP inhibitors like olaparib in preclinical cancer models. This mechanism supports its research use in oncology, particularly for studying transcription-targeted therapies and synthetic lethality.
CAS Number
2088715-91-5
Field of Research
Cell Biology
Smiles
C (=O) (N1C[C@H] (NC=2SC (SCC=3OC (C (C) (C) C) =CN3) =CN2) CCC1) C4=CC=C (NC (C=C) =O) C=C4
Molecular Formula
C26H31N5O3S2
Molecular Weight
525.69
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
BA3848-5MFH290

Popular Products