Products for Research Use Only

Edicotinib HCl

CAT: 0013-GTR19210401-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210401-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Edicotinib (JNJ-40346527) is an orally bioavailable CSF1R/FMS tyrosine kinase inhibitor that blocks CSF1-mediated receptor activation and downstream signaling, suppressing the proliferation of CSF1R-dependent tumor cells. It has been investigated in preclinical in vitro and in vivo studies for cancers like tenosynovial giant cell tumor and glioblastoma.
CAS Number
1559069-92-9
Field of Research
Signal Transduction
Smiles
Cl.CC1 (C) CCC (=CC1) c1nc (ccc1NC (=O) c1ncc ([nH]1) C#N) C1CC (C) (C) OC (C) (C) C1
Molecular Formula
C27H36ClN5O2
Molecular Weight
498.07
Storage Conditions
-20°C
Notes
For research use only.