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Abivertinib HCl

CAT: 0013-GTR19210379-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210379-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Abivertinib (AC0010) is a third-generation EGFR and BTK inhibitor with demonstrated efficacy in research models of acute myeloid leukemia (AML), particularly against FLT3-ITD mutant cells. It shows superior sensitivity compared to ibrutinib in vitro, inducing apoptosis and cell cycle arrest, and holds promise for combination therapies in oncology research.
CAS Number
1557268-90-2
Smiles
Cl.Cl.CN1CCN (CC1) c1ccc (Nc2nc (Oc3cccc (NC (=O) C=C) c3) c3cc[nH]c3n2) cc1F
Molecular Formula
C26H28Cl2FN7O2
Molecular Weight
560.4554
Storage Conditions
-20°C
Notes
For research use only.

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