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AH057

CAT: 0013-GTR19209376-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19209376-01Size:25 mg
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Description
AH057 is a potent and selective small molecule inhibitor of JAK1 and JAK2 kinases. It disrupts the JAK/STAT signaling pathway, demonstrating robust anti-tumor effects by inhibiting proliferation, inducing apoptosis, and blocking cell cycle progression in both cellular and animal models, making it a valuable tool for oncology and immunology research.
CAS Number
118499-11-9
Smiles
N (C (CC) CO) =C1C2=C (C=3C (N2) =CC=C (C) C3) CCC1
Molecular Formula
C17H22N2O
Molecular Weight
270.37
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-[(6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-ylidene)amino]-1-butanol
CAS Number118499-11-9
PubChem CID135521805
IUPAC Name2-[(6-methyl-2,3,4,9-tetrahydrocarbazol-1-ylidene)amino]butan-1-ol
Molecular FormulaC17H22N2O
Molecular Weight270.37
XLogP3.2
Topological Polar Surface Area48.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Heavy Atom Count20
Formal Charge0
Complexity368
SMILES
CCC(CO)N=C1CCCC2=C1NC3=C2C=C(C=C3)C
InChI
InChI=1S/C17H22N2O/c1-3-12(10-20)18-16-6-4-5-13-14-9-11(2)7-8-15(14)19-17(13)16/h7-9,12,19-20H,3-6,10H2,1-2H3
InChIKey
WUPPLXLZQARPFF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-[(6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-ylidene)amino]-1-butanol
CAS: 118499-11-9
CID: 135521805
Formula: C17H22N2O
MW: 270.37
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight270.37
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass270.173213330
Monoisotopic Mass270.173213330
Topological Polar Surface Area48.4 Ų
Heavy Atom Count20
Formal Charge0
Complexity368
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS5813843AH057

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