Products for Research Use Only

NSC145366

CAT: 0013-GTR19208586-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208586-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC145366 is a C-terminal Hsp90 inhibitor that acts allosterically, promoting Hsp90 oligomerization and inhibiting N-terminal ATPase activity without competing for nucleotide binding. This selective client downregulation makes it a valuable research tool for studying Hsp90 function and client protein degradation in cancer biology and neurodegenerative disease models.
CAS Number
1052515-37-3
Smiles
C (C) (C) (C1=CC=C (OCC (CNC (CC (C) (C) C) (C) C) O) C=C1) C2=CC=C (OCC (CNC (CC (C) (C) C) (C) C) O) C=C2.Cl
Molecular Formula
C37H63ClN2O4
Molecular Weight
635.36
Storage Conditions
-20°C
Notes
For research use only.

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