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BPR1K653

CAT: 0013-GTR19208099-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19208099-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BPR1K653 is a potent and selective Aurora-A/B kinase inhibitor with broad-spectrum anticancer activity in vitro, overcoming MDR1-mediated resistance. It induces endoreplication and apoptosis in cancer cells and demonstrates significant in vivo efficacy in xenograft models, including MDR1-positive tumors, supported by favorable pharmacokinetic profiles. This makes it a promising candidate for oncology research, particularly in studying drug-resistant malignancies.
CAS Number
1192754-07-6
Smiles
Cl.CN (C) Cc1ccccc1NC (=O) Nc1ccc (CCNc2ncnc3oc (c (Cl) c23) -c2ccccc2) cc1
Molecular Formula
C30H29ClN6O2
Molecular Weight
541.04
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
T71279-01BPR1K653
MBS3600669-01BPR1K653 hydrochloride

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