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Abeprazan

CAT: 0013-GTR19206571-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206571-01Size:25 mg
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Description
Abeprazan (DWP14012) is a potassium-competitive acid blocker (P-CAB) that reversibly inhibits H+, K+-ATPase without requiring acid activation. It serves as a research tool for investigating gastroesophageal reflux disease (GERD) and peptic ulcers, with studies demonstrating its pharmacological profile in both in vitro and in vivo experimental models.
CAS Number
1902954-60-2
Field of Research
Pharmacology & Drug Discovery
Smiles
CNCc1cn (c (c1OC) -c1ccc (F) cc1F) S (=O) (=O) c1cccc (F) c1
Molecular Formula
C19H17F3N2O3S
Molecular Weight
410.41
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Fexuprazan

Abeprazan is under investigation in clinical trial NCT04341454 (Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Acute or Chronic Gastritis).

CAS Number1902954-60-2
PubChem CID122662112
IUPAC Name1-[5-(2,4-difluorophenyl)-1-(3-fluorophenyl)sulfonyl-4-methoxypyrrol-3-yl]-N-methylmethanamine
Molecular FormulaC19H17F3N2O3S
Molecular Weight410.4
XLogP3.2
Topological Polar Surface Area68.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count28
Formal Charge0
Complexity618
SMILES
CNCC1=CN(C(=C1OC)C2=C(C=C(C=C2)F)F)S(=O)(=O)C3=CC=CC(=C3)F
InChI
InChI=1S/C19H17F3N2O3S/c1-23-10-12-11-24(28(25,26)15-5-3-4-13(20)8-15)18(19(12)27-2)16-7-6-14(21)9-17(16)22/h3-9,11,23H,10H2,1-2H3
InChIKey
OUNXGNDVWVPCOL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Fexuprazan
CAS: 1902954-60-2
CID: 122662112
Formula: C19H17F3N2O3S
MW: 410.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight410.4
XLogP33.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass410.09119807
Monoisotopic Mass410.09119807
Topological Polar Surface Area68.7 Ų
Heavy Atom Count28
Formal Charge0
Complexity618
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
RM-A022600-01Abeprazan
T10221-01Abeprazan hydrochloride
AR-A04906-01Abeprazan HCl
AR-A04908-01Abeprazan Dimer
HY-109079A-01Abeprazan (hydrochloride)
RM-A022603-01Abeprazan Impurity 3
RM-A022601-01Abeprazan Impurity 1
RM-A022602-01Abeprazan Impurity 2
AR-A05203-01Abeprazan-13C-d3
AR-A05205-01N-Nitroso Abeprazan

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