Products for Research Use Only

Apcin-A

CAT: 0013-GTR19206780-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206780-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Apcin-A is a cell-permeable inhibitor of the anaphase-promoting complex/cyclosome (APC/C) that acts by binding to its coactivator Cdc20, thereby blocking the ubiquitination of Cdc20-specific substrates. This compound serves as a valuable chemical probe for cell cycle research and is a key component in the synthesis of the PROTAC molecule CP5V for targeted protein degradation studies.
CAS Number
1683617-62-0
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
NCCCOC (=O) NC (Nc1ncccn1) C (Cl) (Cl) Cl
Molecular Formula
C10H14Cl3N5O2
Molecular Weight
342.61
Storage Conditions
-20°C
Notes
For research use only.

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