Products for Research Use Only

BIIL-260 hydrochloride

CAT: 0013-GTR19206430-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19206430-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BIIL-260 hydrochloride is a potent, orally bioavailable antagonist of the leukotriene B4 (LTB4) receptor. It competitively and reversibly inhibits LTB4-mediated signaling, such as calcium mobilization in human neutrophils. This makes it a valuable research tool for studying LTB4's role in inflammatory diseases like psoriasis, arthritis, and COPD in both cellular and animal models.
CAS Number
192581-24-1
Product Name Alternative
BIIL260 hydrochloride, BIIL-260 Hydrochloride, MOP, NOP, LTB4 receptor1110
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.89% (May vary between batches)
Solubility
DMSO:100 mg/mL (198.8 mM)
Smiles
Cl.N=C (N) C1=CC=C (OCC2=CC=CC (=C2) COC3=CC=C (C=C3) C (C4=CC=C (O) C=C4) (C) C) C=C1
Molecular Formula
C30H31ClN2O3
Molecular Weight
503.03
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

BIIL-260 (hydrochloride)
CAS Number192581-24-1
PubChem CID23292598
IUPAC Name4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidamide;hydrochloride
Molecular FormulaC30H31ClN2O3
Molecular Weight503.0
Topological Polar Surface Area88.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count9
Heavy Atom Count36
Formal Charge0
Complexity644
SMILES
CC(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCC3=CC=CC(=C3)COC4=CC=C(C=C4)C(=N)N.Cl
InChI
InChI=1S/C30H30N2O3.ClH/c1-30(2,24-8-12-26(33)13-9-24)25-10-16-28(17-11-25)35-20-22-5-3-4-21(18-22)19-34-27-14-6-23(7-15-27)29(31)32;/h3-18,33H,19-20H2,1-2H3,(H3,31,32);1H
InChIKey
KYFHIWXKXUSXKB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of BIIL-260 (hydrochloride)
CAS: 192581-24-1
CID: 23292598
Formula: C30H31ClN2O3
MW: 503.0
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight503.0
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count9
Exact Mass502.2023205
Monoisotopic Mass502.2023205
Topological Polar Surface Area88.6 Ų
Heavy Atom Count36
Formal Charge0
Complexity644
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes