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CYP11B2-IN-1

CAT: 0013-GTR19206122-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19206122-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYP11B2-IN-1 is a potent and selective small molecule inhibitor, demonstrating high selectivity for aldosterone synthase (CYP11B2, IC50 = 2.3 nM) over cortisol synthase (CYP11B1, IC50 = 142 nM) . It is a valuable research tool for investigating aldosterone-related pathophysiology in both cellular and animal models of hypertension and heart failure.
CAS Number
1356479-78-1
Product Name Alternative
Cytochrome P450, CYP11B2 IN 1, CYP11B2IN1, CYP-11B2-IN-1, CYP11B2-IN-1
Field of Research
Metabolism Research
Purity
97.89% (May vary between batches)
Solubility
DMSO:50 mg/mL (160.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.42 mM)
Smiles
FC=1C=C2N (C (=NC2=CC1) C=3C=C (C (C) (C) O) C=NC3) C4CC4
Molecular Formula
C18H18FN3O
Molecular Weight
311.35
Storage Conditions
-20°C
Notes
For research use only.

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