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Darbufelone mesylate

CAT: 0013-GTR19206099-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206099-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Darbufelone mesylate (CI-1004 mesylate) is a dual cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) inhibitor, selectively suppressing PGHS-2 (IC50 = 0.19 μM) over PGHS-1 (IC50 = 20 μM) and reducing PGF2α and LTB4 production. This small molecule is a useful research tool for investigating inflammatory pathways in both cellular and animal models of disease.
CAS Number
139340-56-0
Product Name Alternative
CI 1004 Mesylate, CI1004 Mesylate, CI-1004 Mesylate, CI-1004 mesylate, Darbufelone Mesylate, LTB4, PGF2α, Prostaglandin Receptor, ProstaglandinReceptor
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
96.81% (May vary between batches)
Solubility
H2O:<0.1 mg/mL; DMSO:100 mg/mL (233.33 mM)
Smiles
CS (O) (=O) =O.CC (C) (C) c1cc (\C=C2/SC (N) =NC2=O) cc (c1O) C (C) (C) C
Molecular Formula
C19H28N2O5S2
Molecular Weight
428.57
Storage Conditions
-20°C
Notes
For research use only.

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