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GCN2-IN-6

CAT: 0013-GTR19205808-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19205808-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GCN2-IN-6 is a potent, orally bioavailable dual inhibitor of the eIF2α kinases GCN2 and PERK. It demonstrates low nanomolar activity in enzymatic assays and cellular systems, making it a valuable chemical probe for researching the integrated stress response in cancer and neurodegenerative disease models.
CAS Number
2183470-09-7
Product Name Alternative
Inhibit, Eukaryotic Initiation Factor (eIF), Inhibitor, GCN2, cellular assays, GCN2, in-house enzymatic, GCN2, GCN2 IN 6, GCN2IN6, GCN-2-IN-6, GCN2-IN-6, PERK, PERK, cellular assays, PERK, in-house enzymatic
Field of Research
Cell Biology, Signal Transduction
Purity
95.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.3 mM) ; DMSO:250 mg/mL (515.16 mM)
Smiles
Nc1ncc (cn1) C#Cc1c (F) ccc (NS (=O) (=O) c2cc (Cl) cc (CO) c2Cl) c1F
Molecular Formula
C19H12Cl2F2N4O3S
Molecular Weight
485.29
Storage Conditions
-20°C
Notes
For research use only.

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