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JI051

CAT: 0013-GTR19206379-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206379-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JI051 is a small molecule antitumor agent that targets the chaperone protein prohibitin 2 (PHB2) . Its mechanism involves suppressing Hes1 transcription, a key Notch pathway effector, leading to cell cycle arrest and inhibition of proliferation in HEK293 and pancreatic cancer cell lines in vitro.
CAS Number
2234281-75-3
Product Name Alternative
Gammasecretase, Notch, JI 051, JI051, JI-051
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
≥98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.98 mM) ; DMSO:100 mg/mL (274.39 mM)
Smiles
CCOc1ccccc1CCNC (=O) \C=C\c1c[nH]c2c (OC) cccc12
Molecular Formula
C22H24N2O3
Molecular Weight
364.44
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-117113-01JI051
A18774-25JI051 25mg
A18774-100JI051 100mg
A18774-2JI051 2mg
A18774-1JI051 1mg
A18774-50JI051 50mg
A18774-10JI051 10mg
A18774-5JI051 5mg

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