Products for Research Use Only
RegisterLogin

RTC-5

CAT: 0013-GTR19204905-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19204905-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
RTC-5 (TRC-382) is a phenothiazine-derived small molecule with potent anti-cancer activity. It demonstrates efficacy in EGFR-driven xenograft models by concurrently inhibiting the PI3K/AKT and RAS/ERK signaling pathways, making it a useful research tool for studying oncogenic signaling and tumor growth in vitro and in vivo.
CAS Number
1423077-49-9
Product Name Alternative
EGFR, RTC 5, RTC5, RTC-5, TRC 382, TRC382, TRC-382
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.14% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.96 mM) ; DMSO:50 mg/mL (97.86 mM)
Smiles
FC (F) (F) Oc1ccc (cc1) S (=O) (=O) NCCCN1c2ccccc2CCc2ccc (Cl) cc12
Molecular Formula
C24H22ClF3N2O3S
Molecular Weight
510.96
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-4-(trifluoromethoxy)benzenesulfonamide
CAS Number1423077-49-9
PubChem CID71263344
IUPAC NameN-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-(trifluoromethoxy)benzenesulfonamide
Molecular FormulaC24H22ClF3N2O3S
Molecular Weight511.0
XLogP7
Topological Polar Surface Area67
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Heavy Atom Count34
Formal Charge0
Complexity756
SMILES
C1CC2=CC=CC=C2N(C3=C1C=CC(=C3)Cl)CCCNS(=O)(=O)C4=CC=C(C=C4)OC(F)(F)F
InChI
InChI=1S/C24H22ClF3N2O3S/c25-19-9-8-18-7-6-17-4-1-2-5-22(17)30(23(18)16-19)15-3-14-29-34(31,32)21-12-10-20(11-13-21)33-24(26,27)28/h1-2,4-5,8-13,16,29H,3,6-7,14-15H2
InChIKey
QYOJMNDDVVEPFN-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-4-(trifluoromethoxy)benzenesulfonamide
CAS: 1423077-49-9
CID: 71263344
Formula: C24H22ClF3N2O3S
MW: 511.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight511.0
XLogP37
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass510.0991759
Monoisotopic Mass510.0991759
Topological Polar Surface Area67 Ų
Heavy Atom Count34
Formal Charge0
Complexity756
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19225009-01RTC-30
GTR180271485.5 Antibody
GTR19230899-015-LOX-IN-5
GTR19221943-015,5'-Dimethoxysecoisolariciresinol
GTR180271505.5 Antibody
GTR180270775.5 Antibody
GTR19235383-01FABP4/5-IN-5
GTR19182420-015,5'-Dimethoxylariciresinol
GTR19214416-015'-Deoxy-5'-iodo-5-methyluridine
GTR19214414-015'-Azido-5'-deoxy-5-methyluridine

Alternative Products

CatalogName
HY-123952-01RTC-5
A19067-25RTC-5 25mg
A19067-5RTC-5 5mg
A19067-500RTC-5 500mg
A19067-50RTC-5 50mg
A19067-100RTC-5 100mg
A19067-10RTC-5 10mg
A19067-10mM-DRTC-5 10mM * 1mL in DMSO
MBS3843324-01RTC-30
A18865-1RTC-30 1mg

Popular Products