Products for Research Use Only
RegisterLogin

SB-657510

CAT: 0013-GTR19204842-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19204842-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SB-657510 is a potent urotensin-II receptor (UT) antagonist with species-variable binding affinity, exhibiting anti-inflammatory effects by blocking UII-induced mediators in vascular endothelial cells. It has demonstrated therapeutic potential in preclinical models of diabetes-associated atherosclerosis.
CAS Number
474960-44-6
Product Name Alternative
SB 657510, SB657510, SB-657510, urotensin-II (UT), Neurotensin Receptor, NeurotensinReceptor
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.03% (May vary between batches)
Solubility
DMSO:27 mg/mL (53.38 mM)
Smiles
COc1cc (Br) c (cc1OC) S (=O) (=O) Nc1ccc (Cl) c (O[C@@H]2CCN (C) C2) c1
Molecular Formula
C19H22BrClN2O5S
Molecular Weight
505.81
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

SB 657510

a urotensin II antagonist

CAS Number474960-44-6
PubChem CID11272107
IUPAC Name2-bromo-N-[4-chloro-3-[(3R)-1-methylpyrrolidin-3-yl]oxyphenyl]-4,5-dimethoxybenzenesulfonamide
Molecular FormulaC19H22BrClN2O5S
Molecular Weight505.8
XLogP3.9
Topological Polar Surface Area85.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Heavy Atom Count29
Formal Charge0
Complexity637
SMILES
CN1CC[C@H](C1)OC2=C(C=CC(=C2)NS(=O)(=O)C3=C(C=C(C(=C3)OC)OC)Br)Cl
InChI
InChI=1S/C19H22BrClN2O5S/c1-23-7-6-13(11-23)28-16-8-12(4-5-15(16)21)22-29(24,25)19-10-18(27-3)17(26-2)9-14(19)20/h4-5,8-10,13,22H,6-7,11H2,1-3H3/t13-/m1/s1
InChIKey
KQCZCINJGIRLCD-CYBMUJFWSA-N
Chemical Structure
2D Structure
2D structure of SB 657510
CAS: 474960-44-6
CID: 11272107
Formula: C19H22BrClN2O5S
MW: 505.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight505.8
XLogP33.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Exact Mass504.01213
Monoisotopic Mass504.01213
Topological Polar Surface Area85.5 Ų
Heavy Atom Count29
Formal Charge0
Complexity637
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19153626-01SB-269970, SB 269970
GTR19203121-01SB-568849
GTR19234665-01SB 206553
GTR19174839-01SB-505124
GTR19173898-01SB 328437
GTR19171487-01SB-216763
GTR19167903-01SB 239063
GTR19167749-01SB 242084
GTR19164718-01SB-734117
GTR19163440-01SB 242084

Alternative Products

CatalogName
465913-01SB 657510
MBS5753873SB-657510
217783SB-277011-A Dihydrochloride (SB277011A, SB 277011A, Dopamine D3 Receptor Antagonist, SB-277011-A, SB-277011A)
366911-01SB 216763 (SB216763, SB-216763, SCHEMBL30251)
FB32804SB 431542
HHA49832-01SB 225002
FS65161-01SB 408124
FS153504-01SB 590885
FS101433-01SB 242235
BPA49027-01SB-423562

Popular Products