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(Rac) -SIS3 free base

CAT: 0013-GTR19204784-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204784-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SIS3 free base is a selective inhibitor of Smad3 phosphorylation, effectively blocking TGF-β1-induced myofibroblast differentiation. This mechanism supports its use in vitro for studying fibrotic pathways and has shown promise in vivo models of pulmonary and renal fibrosis.
CAS Number
1009104-85-1
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
COc1cc2CCN (Cc2cc1OC) C (=O) \C=C\c1c (-c2ccccc2) n (C) c2ncccc12
Molecular Formula
C28H27N3O3
Molecular Weight
453.53
Storage Conditions
-20°C
Notes
For research use only.

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