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(S) -MCPG

CAT: 0013-GTR19204508-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204508-01Size:5 mg
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Description
(S) -MCPG is a selective antagonist for group I/II metabotropic glutamate receptors (mGluRs) . It is widely used in neuroscience research to study synaptic plasticity, having been shown to inhibit hippocampal long-term potentiation and spatial learning in vivo. This compound serves as a key pharmacological tool for investigating mGluR function in models of neurological disorders.
CAS Number
150145-89-4
Product Name Alternative
MCPG, mGluR, (+) -MCPG, (S) MCPG, (S) MCPG
Field of Research
Neuroscience
Purity
98.72% (May vary between batches)
Solubility
DMSO:5 mg/mL (23.9 mM) ; H2O:80 mg/mL (382.41 mM)
Smiles
C[C@@] (N) (C (O) =O) c1ccc (cc1) C (O) =O
Molecular Formula
C10H11NO4
Molecular Weight
209.20
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(S)-alpha-methyl-4-carboxyphenylglycine

(S)-alpha-methyl-4-carboxyphenylglycine is a non-proteinogenic alpha-amino acid that is alanine in which the alpha-hydrogen is replaced by a 4-carboxyphenyl group (the S-enantiomer). It is a non-selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. It has a role as a metabotropic glutamate receptor antagonist.

CAS Number150145-89-4
PubChem CID446355
IUPAC Name4-[(1S)-1-amino-1-carboxyethyl]benzoic acid
Molecular FormulaC10H11NO4
Molecular Weight209.20
XLogP-2
Topological Polar Surface Area101
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count15
Formal Charge0
Complexity271
SMILES
C[C@](C1=CC=C(C=C1)C(=O)O)(C(=O)O)N
InChI
InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)/t10-/m0/s1
InChIKey
DNCAZYRLRMTVSF-JTQLQIEISA-N
Chemical Structure
2D Structure
2D structure of (S)-alpha-methyl-4-carboxyphenylglycine
CAS: 150145-89-4
CID: 446355
Formula: C10H11NO4
MW: 209.20
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight209.20
XLogP3-2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass209.06880783
Monoisotopic Mass209.06880783
Topological Polar Surface Area101 Ų
Heavy Atom Count15
Formal Charge0
Complexity271
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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