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Homocarbonyltopsentin

CAT: 0013-GTR19204316-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204316-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Homocarbonyltopsentin is a small molecule that binds the TSL2 RNA pentaloop, shifting its conformation to a triloop. This structural change enhances SMN2 exon 7 splicing with an EC50 of 16 μM, making it a valuable research tool for studying spinal muscular atrophy (SMA) therapeutics in vitro.
CAS Number
172286-77-0
Field of Research
Cell Biology, Molecular Biology
Smiles
Oc1ccc2c (c[nH]c2c1) C (=O) c1ncc ([nH]1) C (=O) c1c[nH]c2ccccc12
Molecular Formula
C21H14N4O3
Molecular Weight
370.36
Storage Conditions
-20°C
Notes
For research use only.

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