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PP58

CAT: 0013-GTR19204245-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204245-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PP58 is a small molecule inhibitor targeting platelet-derived growth factor receptor (PDGFR), fibroblast growth factor receptor (FGFR), and Src family kinases. It is a research tool used in vitro and in vivo to study signaling pathways in oncology and angiogenesis.
CAS Number
212391-58-7
Product Name Alternative
FGFR, Src, TNF-α, PP 58, PP58, PP-58, p38 MAPK, p38MAPK, p38, PDGFR
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
99.21% (May vary between batches)
Solubility
DMSO:56.3 mg/mL (123.38 mM)
Smiles
Cn1c2nc (Nc3ccc (OCCN) cc3) ncc2cc (-c2c (Cl) cccc2Cl) c1=O
Molecular Formula
C22H19Cl2N5O2
Molecular Weight
456.32
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-[4-(2-Aminoethoxy)anilino]-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7-one
CAS Number212391-58-7
PubChem CID5327904
IUPAC Name2-[4-(2-aminoethoxy)anilino]-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7-one
Molecular FormulaC22H19Cl2N5O2
Molecular Weight456.3
XLogP3.9
Topological Polar Surface Area93.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count31
Formal Charge0
Complexity648
SMILES
CN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=CC=C3Cl)Cl)NC4=CC=C(C=C4)OCCN
InChI
InChI=1S/C22H19Cl2N5O2/c1-29-20-13(11-16(21(29)30)19-17(23)3-2-4-18(19)24)12-26-22(28-20)27-14-5-7-15(8-6-14)31-10-9-25/h2-8,11-12H,9-10,25H2,1H3,(H,26,27,28)
InChIKey
MAXZESONWXTISA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-[4-(2-Aminoethoxy)anilino]-6-(2,6-dichlorophenyl)-8-methylpyrido[2,3-d]pyrimidin-7-one
CAS: 212391-58-7
CID: 5327904
Formula: C22H19Cl2N5O2
MW: 456.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight456.3
XLogP33.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass455.0915803
Monoisotopic Mass455.0915803
Topological Polar Surface Area93.4 Ų
Heavy Atom Count31
Formal Charge0
Complexity648
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
MBS5754366PP58
A20906-5PP58 5mg
A20906-50PP58 50mg
A20906-2PP58 2mg
A20906-10PP58 10mg
A20906-100PP58 100mg
A20906-25PP58 25mg
A20906-1PP58 1mg
A20906-10mM-DPP58 10mM * 1mL in DMSO
L1565-02CLck (Lck p56, Lymphocyte Cell Specific Protein Tyrosine Kinase, LSK, Oncogene lck, P56 LCK, pp58 lck, Proto-oncogene Tyrosine Protein Kinase LCK, T cell Specific Protein Tyrosine Kinase, T lymphocyte Specific Protein Tyrosine Kinase p56lck, Tyrosine-protein Kinase Lck, YT16)

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