Products for Research Use Only
RegisterLogin

Barbadin

CAT: 0013-GTR19203969-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203969-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Barbadin is a specific inhibitor of β-arrestin/β2-adaptin interactions, blocking agonist-promoted endocytosis of GPCRs like the β2-adrenergic receptor. It has been used in research on obesity, demonstrating in vivo effects such as potentiating lorcaserin-induced weight loss in animal models.
CAS Number
356568-70-2
Product Name Alternative
Barbadin, β-arrestin2, β-arrestin, β-arrestin1
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.93% (May vary between batches)
Solubility
DMSO:60 mg/mL (179.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6 mM)
Smiles
Nn1cnc2scc (-c3ccc (Cc4ccccc4) cc3) c2c1=O
Molecular Formula
C19H15N3OS
Molecular Weight
333.41
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-Amino-5-(4-benzylphenyl)thieno(2,3-d)pyrimidin-4(3H)-one
CAS Number356568-70-2
PubChem CID727640
IUPAC Name3-amino-5-(4-benzylphenyl)thieno[2,3-d]pyrimidin-4-one
Molecular FormulaC19H15N3OS
Molecular Weight333.4
XLogP3.7
Topological Polar Surface Area86.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count24
Formal Charge0
Complexity483
SMILES
C1=CC=C(C=C1)CC2=CC=C(C=C2)C3=CSC4=C3C(=O)N(C=N4)N
InChI
InChI=1S/C19H15N3OS/c20-22-12-21-18-17(19(22)23)16(11-24-18)15-8-6-14(7-9-15)10-13-4-2-1-3-5-13/h1-9,11-12H,10,20H2
InChIKey
OCBXPCSXEQQADU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-Amino-5-(4-benzylphenyl)thieno(2,3-d)pyrimidin-4(3H)-one
CAS: 356568-70-2
CID: 727640
Formula: C19H15N3OS
MW: 333.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight333.4
XLogP33.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass333.09358328
Monoisotopic Mass333.09358328
Topological Polar Surface Area86.9 Ų
Heavy Atom Count24
Formal Charge0
Complexity483
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19217848-01Barbatic acid
GTR19236978-01Barbaloin-related compound A
GTR19228886-01Barbaloin-related compound A
GTR19228887-01Barbaloin-related compound B
GTR19236976-01Barbaloin-related compound B

Alternative Products

CatalogName
525345Barbadin
A18980-10Barbadin 10mg
A18980-2Barbadin 2mg
A18980-5Barbadin 5mg
A18980-1Barbadin 1mg

Popular Products