Products for Research Use Only

Begacestat

CAT: 0013-GTR19203951Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203951Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Begacestat (GSI-953) is a nanomolar-potency gamma-secretase inhibitor that selectively reduces amyloid-beta production over Notch signaling. It has been utilized in cellular and animal models to investigate Alzheimer's disease pathogenesis and has demonstrated effects in reversing memory deficits in preclinical studies.
CAS Number
769169-27-9
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
C ([C@H] (NS (=O) (=O) C=1SC (Cl) =CC1) CO) (C (F) (F) F) C (F) (F) F
Molecular Formula
C9H8ClF6NO3S2
Molecular Weight
391.74
Storage Conditions
-20°C
Notes
For research use only.