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BI8622

CAT: 0013-GTR19203930-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203930-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BI8622 is a specific HUWE1 ubiquitin ligase antagonist that rescues mutant RP2 protein levels in retinal cells and suppresses NLRP3, NLRC4, and AIM2 inflammasome activation. This small molecule is a valuable research tool for studying inherited retinal diseases and inflammasome-related pathologies in cellular models.
CAS Number
1875036-74-0
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
98.28% (May vary between batches)
Smiles
N#CC1 (C=2C=CC=CC2) CCN (C=3N=CN=C (C (=O) NC4=CC=C (C=C4) CN) C3C) CC1
Molecular Formula
C25H26N6O
Molecular Weight
426.51
Storage Conditions
-20°C
Notes
For research use only.

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A18710-100BI8622 100mg
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A18710-1BI8622 1mg
A18710-25BI8622 25mg
A18710-10BI8622 10mg
A18710-5BI8622 5mg
A18710-10mM-DBI8622 10mM * 1mL in DMSO

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