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IRL 2500

CAT: 0013-GTR19203749-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203749-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IRL 2500 is a selective endothelin receptor antagonist, exhibiting potent activity against the ETA receptor (IC50 = 1.3 nM) with significantly lower affinity for the ETB receptor (IC50 = 94 nM) . This small molecule is a valuable research tool for investigating the endothelin system in cardiovascular and pulmonary disease models, both in vitro and in vivo.
CAS Number
169545-27-1
Product Name Alternative
IRL2500, IRL-2500, IRL 2500, Endothelin B receptor, Endothelin A receptor, EndothelinReceptor, Endothelin Receptor, ETB, ETA
Field of Research
Pharmacology & Drug Discovery
Purity
98.29% (May vary between batches)
Solubility
DMSO:93.6 mg/mL (163.16 mM)
Smiles
CN ([C@H] (Cc1ccc (cc1) -c1ccccc1) C (=O) N[C@@H] (Cc1c[nH]c2ccccc12) C (O) =O) C (=O) c1cc (C) cc (C) c1
Molecular Formula
C36H35N3O4
Molecular Weight
573.68
Storage Conditions
-20°C
Notes
For research use only.

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