Products for Research Use Only

L 152804

CAT: 0013-GTR19203693-04Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203693-04Size:25 mg
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Description
L 152804 is a selective Y5 receptor antagonist used in obesity research. It has been shown to reduce food intake and increase energy expenditure, leading to weight loss in diet-induced obese mouse models. This small molecule is a valuable tool for in vitro and in vivo studies of NPY-Y5 receptor function in metabolic disorders.
CAS Number
6508-43-6
Product Name Alternative
NPY5-R, L 152804, Neuropeptide Y Receptor, neuropeptide Y (NPY) Y5 receptor, NeuropeptideYReceptor, L152804, L-152804
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.65% (May vary between batches)
Solubility
DMSO:112.5 mg/mL (307 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.92 mM)
Smiles
CC1 (C) CC (=O) C (C2C3=C (CC (C) (C) CC3=O) Oc3ccccc23) C (=O) C1
Molecular Formula
C23H26O4
Molecular Weight
366.45
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

L-152,804

2-(3,3-dimethyl-1-oxo-4,9-dihydro-2H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione is a member of xanthenes.

CAS Number6508-43-6
PubChem CID3765615
IUPAC Name2-(3,3-dimethyl-1-oxo-4,9-dihydro-2H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione
Molecular FormulaC23H26O4
Molecular Weight366.4
XLogP3.4
Topological Polar Surface Area60.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count27
Formal Charge0
Complexity707
SMILES
CC1(CC(=O)C(C(=O)C1)C2C3=CC=CC=C3OC4=C2C(=O)CC(C4)(C)C)C
InChI
InChI=1S/C23H26O4/c1-22(2)9-14(24)20(15(25)10-22)19-13-7-5-6-8-17(13)27-18-12-23(3,4)11-16(26)21(18)19/h5-8,19-20H,9-12H2,1-4H3
InChIKey
XQDXIHYKAGHZRX-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of L-152,804
CAS: 6508-43-6
CID: 3765615
Formula: C23H26O4
MW: 366.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight366.4
XLogP33.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass366.18310931
Monoisotopic Mass366.18310931
Topological Polar Surface Area60.4 Ų
Heavy Atom Count27
Formal Charge0
Complexity707
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes