Products for Research Use Only
RegisterLogin

LP-922761

CAT: 0013-GTR19203623-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203623-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LP-922761 is a potent, selective, and orally bioavailable inhibitor of both AAK1 and BIKE kinases. This small molecule is a valuable research tool for investigating clathrin-mediated endocytosis and BMP signaling in cellular and animal models of neurological disorders and pain.
CAS Number
1454808-95-7
Product Name Alternative
AP2 associated kinase 1, AP2associatedkinase1, BIKE, AAK1, AAK1 (AP2associatedkinase1), AAK1 (AP2 associated kinase 1), LP922761, LP-922761, LP 922761
Field of Research
Neuroscience
Purity
97.19% (May vary between batches)
Solubility
DMSO:1 mg/mL (2.44 mM)
Smiles
CN (CCNc1ccc2ncc (-c3ccc (cc3) C (N) =O) n2n1) C (=O) OC (C) (C) C
Molecular Formula
C21H26N6O3
Molecular Weight
410.47
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

tert-Butyl(2-((3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl)amino)ethyl)(methyl)carbamate
CAS Number1454808-95-7
PubChem CID86696405
IUPAC Nametert-butyl N-[2-[[3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl]amino]ethyl]-N-methylcarbamate
Molecular FormulaC21H26N6O3
Molecular Weight410.5
XLogP2.1
Topological Polar Surface Area115
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Heavy Atom Count30
Formal Charge0
Complexity602
SMILES
CC(C)(C)OC(=O)N(C)CCNC1=NN2C(=NC=C2C3=CC=C(C=C3)C(=O)N)C=C1
InChI
InChI=1S/C21H26N6O3/c1-21(2,3)30-20(29)26(4)12-11-23-17-9-10-18-24-13-16(27(18)25-17)14-5-7-15(8-6-14)19(22)28/h5-10,13H,11-12H2,1-4H3,(H2,22,28)(H,23,25)
InChIKey
YNQNYIHMAZLJAV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of tert-Butyl(2-((3-(4-carbamoylphenyl)imidazo[1,2-b]pyridazin-6-yl)amino)ethyl)(methyl)carbamate
CAS: 1454808-95-7
CID: 86696405
Formula: C21H26N6O3
MW: 410.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight410.5
XLogP32.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Exact Mass410.20663871
Monoisotopic Mass410.20663871
Topological Polar Surface Area115 Ų
Heavy Atom Count30
Formal Charge0
Complexity602
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19222067LP-184
GTR19187759-01LP-284
GTR19234352-01LP-6
GTR19164704-01LP-261
GTR19258655-01Lp (a) -IN-6
GTR19258392-01Lp (a) -IN-7
GTR19197247-01LP-403812
GTR19193701LP-20
GTR19193699LP-360924
GTR19168482-01LP-211

Alternative Products

CatalogName
BUP05749-01LP-922761
MBS5804832LP-922761 hydrate
HY-120179ALP-922761 (hydrate)
030400LPA (Apolipoprotein (a), LP, Lp (a) )
A2299-80AApolipoprotein Lp (a) (Apo Lp-a)
KAI-044Lp (a)
A2299-80Apolipoprotein Lp (a) (Apo Lp-a) discontinued
MBS6463816-01Apolipoprotein Lp(a) (Apo Lp-a) (PE)
MBS6463809-01Apolipoprotein Lp(a) (Apo Lp-a) (HRP)
MBS6463807-01Apolipoprotein Lp(a) (Apo Lp-a) (Biotin)

Popular Products