LX2761

CAT: 0013-GTR19203617-02Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19203617-02Size:50 mg

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Description

LX2761 is a potent, chemically stable dual inhibitor of SGLT1 and SGLT2 (IC50 ~2-3 nM) . It exhibits selective SGLT1 inhibition in the GI tract, making it a valuable research tool for studying glucose homeostasis and diabetes in both cellular and animal models.

CAS Number

1610954-97-6

Field of Research

Pharmacology & Drug Discovery

Smiles

O[C@H]1[C@@H] (O[C@H] (SC) [C@@H] (O) [C@@H]1O) C2=CC (CC3=CC=C (CCCC (NC (C (NCCN (C) C) =O) (C) C) =O) C=C3) =C (C) C=C2

Molecular Formula

C32H47N3O6S

Molecular Weight

601.80

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

LX2761

inhibits sodium-glucose transporter 1 (SGLT1); structure in first source

CAS Number	1610954-97-6
PubChem CID	76070894
IUPAC Name	N-[2-(dimethylamino)ethyl]-2-methyl-2-[4-[4-[[2-methyl-5-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]phenyl]methyl]phenyl]butanoylamino]propanamide
Molecular Formula	C32H47N3O6S
Molecular Weight	601.8
XLogP	2.5
Topological Polar Surface Area	157
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	13
Heavy Atom Count	42
Formal Charge	0
Complexity	852

SMILES

CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)SC)O)O)O)CC3=CC=C(C=C3)CCCC(=O)NC(C)(C)C(=O)NCCN(C)C

InChI

InChI=1S/C32H47N3O6S/c1-20-10-15-23(29-27(38)26(37)28(39)30(41-29)42-6)19-24(20)18-22-13-11-21(12-14-22)8-7-9-25(36)34-32(2,3)31(40)33-16-17-35(4)5/h10-15,19,26-30,37-39H,7-9,16-18H2,1-6H3,(H,33,40)(H,34,36)/t26-,27-,28+,29+,30-/m1/s1

InChIKey

BNPZTRDIESRGTC-IXYVTWBDSA-N

Chemical Structure

2D Structure

CAS: 1610954-97-6

CID: 76070894

Formula: C32H47N3O6S

MW: 601.8

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	601.8
XLogP3	2.5
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	13
Exact Mass	601.31855740
Monoisotopic Mass	601.31855740
Topological Polar Surface Area	157 Å²
Heavy Atom Count	42
Formal Charge	0
Complexity	852
Isotope Atom Count	0
Defined Atom Stereocenter Count	5
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
MBS3602329-01	LX2761
A20597-10	LX2761 10mg
A20597-1	LX2761 1mg
A20597-100	LX2761 100mg
A20597-50	LX2761 50mg
A20597-25	LX2761 25mg
A20597-5	LX2761 5mg

LX2761

Chemical Information

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