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Merestinib dihydrochloride

CAT: 0013-GTR19203609-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203609-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Merestinib dihydrochloride is an orally bioavailable small molecule inhibitor targeting kinases including MET, AXL, RON, and MKNK1/2. It demonstrates antitumor activity in preclinical studies, showing efficacy against tumors harboring NTRK fusions in both cellular assays and in vivo models.
CAS Number
1206801-37-7
Product Name Alternative
TEK, TAM Receptor, TAMReceptor, Tyrosine Kinases, TyrosineKinases, MKNK1/2, LY 2801653, LY 2801653 dihydrochloride, LY2801653, LY-2801653 Dihydrochloride, LY-2801653, LY2801653 dihydrochloride, MST1R, FLT3, DDR1/2, HGFR, MERTK, Merestinib, AXL, cMet/HGFR, c-Met, cMet
Field of Research
Cardiovascular Research, Signal Transduction
Solubility
DMSO:80 mg/mL (127.91 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.28 mM)
Smiles
Cc1ccc (C (=O) Nc2ccc (Oc3cc4cnn (C) c4cc3-c3cn[nH]c3) c (F) c2) c (=O) n1-c1ccc (F) cc1.Cl.Cl
Molecular Formula
C30H24Cl2F2N6O3
Molecular Weight
625.45
Storage Conditions
-20°C
Notes
For research use only.

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