Products for Research Use Only
RegisterLogin

DC_517

CAT: 0013-GTR19203440-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203440-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DC_517 is a potent small molecule inhibitor of DNA methyltransferase 1 (DNMT1), exhibiting an IC50 of 1.7 μM and a Kd of 0.91 μM. This compound is a valuable research tool for studying DNA methylation in epigenetics, cancer biology, and developmental research, applicable in both cellular and biochemical assays.
CAS Number
500017-70-9
Field of Research
Epigenetics & Chromatin
Smiles
CC (C) NCC (O) COC (Cn1c2ccccc2c2ccccc12) Cn1c2ccccc2c2ccccc12
Molecular Formula
C33H35N3O2
Molecular Weight
505.65
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-[1,3-Di(carbazol-9-yl)propan-2-yloxy]-3-(propan-2-ylamino)propan-2-ol

DC_517 is a member of the class of carbazoles that is 1,3-di(9H-carbazol-9-yl)propan-2-ol in which the hydroxy group is replaced by a 2-hydroxy-3-[(propan-2-yl)amino]propoxy group. It is a DNA methyltransferase 1 inhibitor (IC50 = 1.7 M). It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.1.1.37 [DNA (cytosine-5-)-methyltransferase] inhibitor. It is an ether, a secondary alcohol, a member of carbazoles, a secondary amino compound and a tertiary amino compound.

CAS Number500017-70-9
PubChem CID3713657
IUPAC Name1-[1,3-di(carbazol-9-yl)propan-2-yloxy]-3-(propan-2-ylamino)propan-2-ol
Molecular FormulaC33H35N3O2
Molecular Weight505.6
XLogP6
Topological Polar Surface Area51.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count10
Heavy Atom Count38
Formal Charge0
Complexity654
SMILES
CC(C)NCC(COC(CN1C2=CC=CC=C2C3=CC=CC=C31)CN4C5=CC=CC=C5C6=CC=CC=C64)O
InChI
InChI=1S/C33H35N3O2/c1-23(2)34-19-24(37)22-38-25(20-35-30-15-7-3-11-26(30)27-12-4-8-16-31(27)35)21-36-32-17-9-5-13-28(32)29-14-6-10-18-33(29)36/h3-18,23-25,34,37H,19-22H2,1-2H3
InChIKey
BLTONWSCODZCNA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-[1,3-Di(carbazol-9-yl)propan-2-yloxy]-3-(propan-2-ylamino)propan-2-ol
CAS: 500017-70-9
CID: 3713657
Formula: C33H35N3O2
MW: 505.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight505.6
XLogP36
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count10
Exact Mass505.27292737
Monoisotopic Mass505.27292737
Topological Polar Surface Area51.4 Ų
Heavy Atom Count38
Formal Charge0
Complexity654
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19200384-01DC_501

Alternative Products

CatalogName
BA4648-2DC_517

Popular Products