Products for Research Use Only

PF-04991532

CAT: 0013-GTR19203291-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203291-01Size:1 mg
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Description
PF-04991532 is a hepatoselective glucokinase activator with EC50 values of 80 nM (human) and 100 nM (rat) . It has demonstrated efficacy in reducing plasma glucose and AMP levels in the diabetic Goto-Kakizaki rat model, supporting its use in diabetes and metabolic disorder research.
CAS Number
1215197-37-7
Product Name Alternative
Glucokinase, glucokinase in human, PF04991532, PF-04991532, PF 04991532
Field of Research
Metabolism Research
Purity
99.99% (May vary between batches)
Solubility
DMSO:100 mg/mL (252.3 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.33 mM)
Smiles
[C@H] (CC1CCCC1) (C (NC2=CC=C (C (O) =O) C=N2) =O) N3C=C (C (F) (F) F) N=C3
Molecular Formula
C18H19F3N4O3
Molecular Weight
396.36
Storage Conditions
-20°C
Notes
For research use only.