Products for Research Use Only

SMER18

CAT: 0013-GTR19203082-05Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203082-05Size:25 mg
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Description
SMER18 is a small molecule autophagy inducer that functions independently of mTOR, thereby enhancing the effects of rapamycin. It serves as a valuable research tool for investigating autophagy mechanisms and their implications in neurodegenerative disease models, both in vitro and in vivo.
CAS Number
944153-47-3
Product Name Alternative
Autophagy, SMER 18, SMER18, SMER-18
Field of Research
Cell Biology
Purity
97.27% (May vary between batches)
Solubility
DMSO:80 mg/mL (278.03 mM)
Smiles
C\C (Nc1cccc (O) c1) =C\C (=O) c1ccc (Cl) cc1
Molecular Formula
C16H14ClNO2
Molecular Weight
287.74
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(Z)-1-(4-chlorophenyl)-3-(3-hydroxyanilino)but-2-en-1-one
CAS Number944153-47-3
PubChem CID877863
IUPAC Name(Z)-1-(4-chlorophenyl)-3-(3-hydroxyanilino)but-2-en-1-one
Molecular FormulaC16H14ClNO2
Molecular Weight287.74
XLogP4.6
Topological Polar Surface Area49.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count20
Formal Charge0
Complexity361
SMILES
C/C(=C/C(=O)C1=CC=C(C=C1)Cl)/NC2=CC(=CC=C2)O
InChI
InChI=1S/C16H14ClNO2/c1-11(18-14-3-2-4-15(19)10-14)9-16(20)12-5-7-13(17)8-6-12/h2-10,18-19H,1H3/b11-9-
InChIKey
SNEQASFEVWLKOJ-LUAWRHEFSA-N
Chemical Structure
2D Structure
2D structure of (Z)-1-(4-chlorophenyl)-3-(3-hydroxyanilino)but-2-en-1-one
CAS: 944153-47-3
CID: 877863
Formula: C16H14ClNO2
MW: 287.74
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight287.74
XLogP34.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass287.0713064
Monoisotopic Mass287.0713064
Topological Polar Surface Area49.3 Ų
Heavy Atom Count20
Formal Charge0
Complexity361
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes