Products for Research Use Only

TC13172

CAT: 0013-GTR19203026Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19203026Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TC13172 is a potent, covalent, and selective MLKL inhibitor that blocks necroptosis with an EC50 of 2 nM in HT-29 cells. It prevents MLKL oligomerization and membrane translocation, making it a valuable chemical probe for studying necroptosis in inflammatory and degenerative disease research.
CAS Number
2093393-05-4
Field of Research
Signal Transduction
Smiles
O=C1C2=C (N=C (N2C) S (=O) (=O) C) N (C (=O) N1C) CC#CC=3C=CC=C (O) C3
Molecular Formula
C17H16N4O5S
Molecular Weight
388.4
Storage Conditions
-20°C
Notes
For research use only.