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TRAF-STOP inhibitor 6877002

CAT: 0013-GTR19202974-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19202974-01Size:100 mg
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Description
TRAF-STOP inhibitor 6877002 is a selective small molecule that disrupts the CD40-TRAF6 interaction. It has been shown in research to attenuate macrophage activation and proliferation in atherosclerotic plaques, as well as reduce leukocyte recruitment in relevant in vivo models of inflammation.
CAS Number
433249-94-6
Product Name Alternative
TRAF-STOP inhibitor 6877002, NF-kB, NFkB, NFκB, NF-κB, CD40-TRAF6 inhibitor, CD40-TRAF6 interaction
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.65% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.92 mM) ; DMSO:112.5 mg/mL (447.64 mM)
Smiles
Cc1ccc (C) c (N\C=C\C (=O) c2ccccc2) c1
Molecular Formula
C17H17NO
Molecular Weight
251.32
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

TRAF-STOP inhibitor 6877002
CAS Number433249-94-6
PubChem CID2291556
IUPAC Name(E)-3-(2,5-dimethylanilino)-1-phenylprop-2-en-1-one
Molecular FormulaC17H17NO
Molecular Weight251.32
XLogP4.7
Topological Polar Surface Area29.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Heavy Atom Count19
Formal Charge0
Complexity317
SMILES
CC1=CC(=C(C=C1)C)N/C=C/C(=O)C2=CC=CC=C2
InChI
InChI=1S/C17H17NO/c1-13-8-9-14(2)16(12-13)18-11-10-17(19)15-6-4-3-5-7-15/h3-12,18H,1-2H3/b11-10+
InChIKey
SARYOFMRLSHZFE-ZHACJKMWSA-N
Chemical Structure
2D Structure
2D structure of TRAF-STOP inhibitor 6877002
CAS: 433249-94-6
CID: 2291556
Formula: C17H17NO
MW: 251.32
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight251.32
XLogP34.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count4
Exact Mass251.131014166
Monoisotopic Mass251.131014166
Topological Polar Surface Area29.1 Ų
Heavy Atom Count19
Formal Charge0
Complexity317
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
HY-110247-01TRAF-STOP inhibitor 6877002
A19758-25TRAF-STOP inhibitor 6877002 25mg
A19758-10TRAF-STOP inhibitor 6877002 10mg
A19758-100TRAF-STOP inhibitor 6877002 100mg
A19758-50TRAF-STOP inhibitor 6877002 50mg
A19758-5TRAF-STOP inhibitor 6877002 5mg
A19758-10mM-DTRAF-STOP inhibitor 6877002 10mM * 1mL in DMSO
NBP2-26506TRAF-6 Inhibitor Peptide Set
362283BIRC2 (Baculoviral IAP Repeat Containing Protein 2, API1, HIAP2, Hiap-2, MIHB, RNF48, cIAP1, Inhibitor of apoptosis protein 2, NFR2-TRAF Signalling Complex Protein, Apoptosis Inhibitor 1)
B2050-01LBIRC3 (IAP2, cellular, cIAP2, Inhibitor of Apoptosis 2, API2, Baculoviral IAP Repeat-containing 3, CIAP2, HAIP1, HIAP1, MIHC, TNFR2-TRAF Signaling Complex Protein)

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