Products for Research Use Only

UPGL00004

CAT: 0013-GTR19202951-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19202951-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UPGL00004 is a potent and selective glutaminase C (GAC) inhibitor, demonstrating high affinity with a Kd of 27 nM and inhibiting GAC activity with an IC50 of 29 nM. It effectively suppresses the proliferation of aggressive triple-negative breast cancer cells in vitro, making it a valuable tool for studying cancer metabolism and therapeutic targeting.
CAS Number
1890169-95-5
Product Name Alternative
Glutaminase C, UPGL 00004, UPGL00004, UPGL-00004
Field of Research
Protein Biochemistry
Purity
97.44% (May vary between batches)
Solubility
DMSO:112.5 mg/mL (210.41 mM)
Smiles
O=C (Cc1ccccc1) Nc1nnc (NC2CCN (CC2) c2nnc (NC (=O) Cc3ccccc3) s2) s1
Molecular Formula
C25H26N8O2S2
Molecular Weight
534.66
Storage Conditions
-20°C
Notes
For research use only.