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Vecabrutinib

CAT: 0013-GTR19202944-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19202944-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Vecabrutinib (SNS-062) is a potent, noncovalent dual inhibitor of BTK and ITK with respective Kd values of 0.3 nM and 2.2 nM, and an IC50 of 24 nM against ITK. This investigational compound is utilized in preclinical research for studying B-cell and T-cell signaling pathways in both in vitro and in vivo models of autoimmune and hematological disorders.
CAS Number
1510829-06-7
Product Name Alternative
BTK, ITK, TyrosineKinases, Tyrosine Kinases, Vecabrutinib, SNS 062, SNS062, SNS-062
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.74% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.55 mM) ; DMSO:112.5 mg/mL (212.3 mM)
Smiles
NC (=O) [C@H]1CCN (C[C@@H]1N1CCC[C@@H] (Nc2cc (Cl) cc (c2) C (F) (F) F) C1=O) c1ncnc (N) c1F
Molecular Formula
C22H24ClF4N7O2
Molecular Weight
529.92
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
MBS5755691Vecabrutinib
A17189-25Vecabrutinib 25mg
A17189-5Vecabrutinib 5mg
A17189-50Vecabrutinib 50mg
A17189-10Vecabrutinib 10mg
AR-R02027-01Vecabrutinib-d4
A17189-1Vecabrutinib 1mg
A17189-100Vecabrutinib 100mg

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