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PF-06273340

CAT: 0013-GTR19202553Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19202553Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-06273340 is a potent, selective, and peripherally restricted pan-Trk inhibitor with single-digit nM IC50 values against TrkA, TrkB, and TrkC. Its pharmacokinetic profile, characterized by low hepatic metabolism, active efflux transport, and moderate permeability, supports its utility in preclinical research for investigating peripheral Trk-mediated pathways in pain and oncology models.
CAS Number
1402438-74-7
Product Name Alternative
PF 6273340, PF 06273340, PF06273340, PF-06273340, PF6273340, PF-6273340, Trkreceptor, Tropomyosin related kinase receptor, Trk Receptor, Trk receptor, TrkC, TrkB, TrkA, inhibit, Inhibitor
Field of Research
Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
Ethanol:1 mg/mL (2.08 mM) ; DMSO:90 mg/mL (187.53 mM) ; H2O:Insoluble
Smiles
C (=O) (C=1C=2C (N (C (CO) (C) C) C1) =NC (N) =NC2) C=3C=C (NC (CC4=CC=C (Cl) C=N4) =O) C=NC3
Molecular Formula
C23H22ClN7O3
Molecular Weight
479.92
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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C13399PF-06273340
CGC43874PF 06273340
A22377-50PF-06273340 50mg
A22377-5PF-06273340 5mg
A22377-10PF-06273340 10mg
A22377-1PF-06273340 1mg
A22377-100PF-06273340 100mg
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