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Drinabant

CAT: 0013-GTR19201597-04Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19201597-04Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Drinabant
CAS Number
358970-97-5
Product Name Alternative
CB1R, Drinabant, Cannabinoid Receptor, CannabinoidReceptor, AVE1625, AVE-1625, AVE 1625
Field of Research
Pharmacology & Drug Discovery
Purity
99.80% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.02 mM) ; DMSO:50 mg/mL (100.53 mM)
Smiles
C (N1CC (N (S (C) (=O) =O) C2=CC (F) =CC (F) =C2) C1) (C3=CC=C (Cl) C=C3) C4=CC=C (Cl) C=C4
Molecular Formula
C23H20Cl2F2N2O2S
Molecular Weight
497.38
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Drinabant

AVE-1625 is an oral selective and potent antagonist of cannabinoid 1 (CB1) receptors having the same mechanism of action as rimonabant. It is currently developed in obesity and its associated comorbidities. AVE-1625 is also being developed for the treatment of Alzheimer disease.

CAS Number358970-97-5
PubChem CID10278470
IUPAC NameN-[1-[bis(4-chlorophenyl)methyl]azetidin-3-yl]-N-(3,5-difluorophenyl)methanesulfonamide
Molecular FormulaC23H20Cl2F2N2O2S
Molecular Weight497.4
XLogP5.6
Topological Polar Surface Area49
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count32
Formal Charge0
Complexity686
SMILES
CS(=O)(=O)N(C1CN(C1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)C4=CC(=CC(=C4)F)F
InChI
InChI=1S/C23H20Cl2F2N2O2S/c1-32(30,31)29(21-11-19(26)10-20(27)12-21)22-13-28(14-22)23(15-2-6-17(24)7-3-15)16-4-8-18(25)9-5-16/h2-12,22-23H,13-14H2,1H3
InChIKey
IQQBRKLVEALROM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Drinabant
CAS: 358970-97-5
CID: 10278470
Formula: C23H20Cl2F2N2O2S
MW: 497.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight497.4
XLogP35.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass496.0590608
Monoisotopic Mass496.0590608
Topological Polar Surface Area49 Ų
Heavy Atom Count32
Formal Charge0
Complexity686
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
MBS3616069-01Drinabant

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