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Acifran

CAT: 0013-GTR19201472-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19201472-01Size:1 mg
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Description
Acifran (AY 25712) is a small molecule agonist for the HM74A/GPR109A and GPR109B receptors. It exhibits antihyperlipidemic properties and is utilized in research to investigate lipid metabolism, particularly in the context of in vitro receptor activation studies and in vivo models of dyslipidemia.
CAS Number
72420-38-3
Product Name Alternative
GPR109A, GPR109B, Acifran, AY 25712, AY25712, AY-25712
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
98.65% (May vary between batches)
Solubility
Ethanol:19.6 mg/mL (89.82 mM) ; DMSO:19.6 mg/mL (89.82 mM)
Smiles
CC1 (OC (=CC1=O) C (O) =O) c1ccccc1
Molecular Formula
C12H10O4
Molecular Weight
218.21
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Acifran

Acifran is an agonist of niacin receptors capable of mimicking niacin's ability to increase high-density lipoprotein (HDL). Acifran produces these effects at lower doses and without the skin flushing side-effects associated with niacin treatment.

CAS Number72420-38-3
PubChem CID51576
IUPAC Name5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
Molecular FormulaC12H10O4
Molecular Weight218.20
XLogP1.7
Topological Polar Surface Area63.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count16
Formal Charge0
Complexity352
SMILES
CC1(C(=O)C=C(O1)C(=O)O)C2=CC=CC=C2
InChI
InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)
InChIKey
DFDGRKNOFOJBAJ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Acifran
CAS: 72420-38-3
CID: 51576
Formula: C12H10O4
MW: 218.20
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight218.20
XLogP31.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass218.05790880
Monoisotopic Mass218.05790880
Topological Polar Surface Area63.6 Ų
Heavy Atom Count16
Formal Charge0
Complexity352
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
1762/50Acifran
HY-107579RAcifran (Standard)

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