Products for Research Use Only

ML289

CAT: 0013-GTR19201127-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19201127-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML289 (VU0463597) is a brain-penetrant, selective negative allosteric modulator of the mGlu3 receptor with an IC50 of 0.66 μM. It exhibits >15-fold selectivity over mGlu2 and is inactive at mGlu5. This tool compound is useful for investigating mGlu3's role in CNS disorders in both cellular and animal models.
CAS Number
1382481-79-9
Product Name Alternative
VU 0463597, VU0463597, VU-0463597, ML289, ML-289, ML 289, mGluR3
Field of Research
Neuroscience
Purity
99.09% (May vary between batches)
Solubility
DMSO:225 mg/mL (643.92 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (14.31 mM)
Smiles
COc1ccc (cc1) C#Cc1ccc (cc1) C (=O) N1CCC[C@@H] (CO) C1
Molecular Formula
C22H23NO3
Molecular Weight
349.42
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T23000-01ML289

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