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TT-10

CAT: 0013-GTR19210255-05Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210255-05Size:25 mg
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Description
TT-10 (TAZ-K) is a small molecule activator of the YAP-TEAD transcriptional complex. It is a valuable research tool for studying cardiac regeneration and repair in models of heart disease involving cardiomyocyte loss, with applications in both in vitro and in vivo experimental systems.
CAS Number
2230640-94-3
Product Name Alternative
TAZ-K, TT 10, TT10, TT-10, YAP–TEAD
Field of Research
Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
2% DMSO+40% PEG300+5% Tween 80+53% Saline:1.25 mg/mL (4.41 mM) ; DMSO:60 mg/mL (211.75 mM)
Smiles
Nc1nc (NCC=C) sc1C (=O) c1ccc (F) s1
Molecular Formula
C11H10FN3OS2
Molecular Weight
283.35
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(2-(Allylamino)-4-aminothiazol-5-yl)(5-fluorothiophen-2-yl)methanone
CAS Number2230640-94-3
PubChem CID134827875
IUPAC Name[4-amino-2-(prop-2-enylamino)-1,3-thiazol-5-yl]-(5-fluorothiophen-2-yl)methanone
Molecular FormulaC11H10FN3OS2
Molecular Weight283.3
XLogP4.2
Topological Polar Surface Area124
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Heavy Atom Count18
Formal Charge0
Complexity331
SMILES
C=CCNC1=NC(=C(S1)C(=O)C2=CC=C(S2)F)N
InChI
InChI=1S/C11H10FN3OS2/c1-2-5-14-11-15-10(13)9(18-11)8(16)6-3-4-7(12)17-6/h2-4H,1,5,13H2,(H,14,15)
InChIKey
GVYPHJQPOHDZEI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (2-(Allylamino)-4-aminothiazol-5-yl)(5-fluorothiophen-2-yl)methanone
CAS: 2230640-94-3
CID: 134827875
Formula: C11H10FN3OS2
MW: 283.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight283.3
XLogP34.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass283.02493246
Monoisotopic Mass283.02493246
Topological Polar Surface Area124 Ų
Heavy Atom Count18
Formal Charge0
Complexity331
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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