Products for Research Use Only
RegisterLogin

LY3325656

CAT: 0013-GTR19209997-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19209997-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LY3325656 is a GPR142 agonist with demonstrated anti-diabetic efficacy in preclinical models, showing suitable ADME/PK for human use. It is the first molecule of its class to enter Phase 1 clinical trials for Type 2 diabetes, following studies confirming its in vitro receptor activation and in vivo glucose-lowering effects in animal studies.
CAS Number
1998714-25-2
Smiles
CC1=C (N (C) C=N1) C=2NC (=NN2) [C@@H]3C[C@H] (N (C (=O) C4=CC (C (F) (F) F) =CC=C4) C) CCO3
Molecular Formula
C21H23F3N6O2
Molecular Weight
448.44
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

US10196385, Example 1
CAS Number1998714-25-2
PubChem CID135205863
IUPAC NameN-[(2S,4R)-2-[3-(3,5-dimethylimidazol-4-yl)-1H-1,2,4-triazol-5-yl]oxan-4-yl]-N-methyl-3-(trifluoromethyl)benzamide
Molecular FormulaC21H23F3N6O2
Molecular Weight448.4
XLogP2.5
Topological Polar Surface Area88.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Heavy Atom Count32
Formal Charge0
Complexity668
SMILES
CC1=C(N(C=N1)C)C2=NNC(=N2)[C@@H]3C[C@@H](CCO3)N(C)C(=O)C4=CC(=CC=C4)C(F)(F)F
InChI
InChI=1S/C21H23F3N6O2/c1-12-17(29(2)11-25-12)19-26-18(27-28-19)16-10-15(7-8-32-16)30(3)20(31)13-5-4-6-14(9-13)21(22,23)24/h4-6,9,11,15-16H,7-8,10H2,1-3H3,(H,26,27,28)/t15-,16+/m1/s1
InChIKey
LEKZBCFOSTUBJZ-CVEARBPZSA-N
Chemical Structure
2D Structure
2D structure of US10196385, Example 1
CAS: 1998714-25-2
CID: 135205863
Formula: C21H23F3N6O2
MW: 448.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight448.4
XLogP32.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass448.18345848
Monoisotopic Mass448.18345848
Topological Polar Surface Area88.9 Ų
Heavy Atom Count32
Formal Charge0
Complexity668
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
T70005-01LY3325656

Popular Products