Products for Research Use Only

SMN-C3

CAT: 0013-GTR19204776-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204776-02Size:5 mg
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Description
SMN-C3 (MV8T2MCK57) is an orally bioavailable small molecule that modulates SMN2 pre-mRNA splicing to increase functional SMN protein levels. It is a research tool for investigating SMA therapeutics, with demonstrated activity in both cellular assays and animal models of spinal muscular atrophy.
CAS Number
1449597-34-5
Product Name Alternative
MV8T2MCK57, DNA Synthesis, DNASynthesis, RNASynthesis, RNA Synthesis, SMN2, SMN-C3, SMN
Field of Research
Cell Biology, Molecular Biology
Purity
97.60% (May vary between batches)
Solubility
DMSO:2 mg/mL (4.8 mM)
Smiles
CCN1CCC (CC1) c1cc (C) c2nc (cc (=O) n2c1) -c1cc2c (C) nc (C) cn2n1
Molecular Formula
C24H28N6O
Molecular Weight
416.52
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Unii-MV8T2mck57
CAS Number1449597-34-5
PubChem CID89741632
IUPAC Name2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-(1-ethylpiperidin-4-yl)-9-methylpyrido[1,2-a]pyrimidin-4-one
Molecular FormulaC24H28N6O
Molecular Weight416.5
XLogP1.5
Topological Polar Surface Area66.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count31
Formal Charge0
Complexity865
SMILES
CCN1CCC(CC1)C2=CN3C(=O)C=C(N=C3C(=C2)C)C4=NN5C=C(N=C(C5=C4)C)C
InChI
InChI=1S/C24H28N6O/c1-5-28-8-6-18(7-9-28)19-10-15(2)24-26-20(12-23(31)29(24)14-19)21-11-22-17(4)25-16(3)13-30(22)27-21/h10-14,18H,5-9H2,1-4H3
InChIKey
ZACWYYKZMLGOTG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Unii-MV8T2mck57
CAS: 1449597-34-5
CID: 89741632
Formula: C24H28N6O
MW: 416.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight416.5
XLogP31.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass416.23245954
Monoisotopic Mass416.23245954
Topological Polar Surface Area66.1 Ų
Heavy Atom Count31
Formal Charge0
Complexity865
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes