Products for Research Use Only
RegisterLogin

AS 1892802

CAT: 0013-GTR19201554-03Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19201554-03Size:1 ml x 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AS 1892802 is a potent and selective ROCK inhibitor, with IC50 values of 52 nM (human ROCK2), 57 nM (rat ROCK2), and 122 nM (human ROCK1) . Its antinociceptive onset matches Tramadol and Diclofenac, supporting its use in research on cardiovascular function, neuronal regeneration, and pain mechanisms in both cellular and animal models.
CAS Number
928320-12-1
Product Name Alternative
ROCK, AS 1892802, AS1892802, AS-1892802
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.90% (May vary between batches)
Solubility
Ethanol:7.5 mg/mL (22.5 mM) ; DMSO:40 mg/mL (119.98 mM)
Smiles
N (C (N[C@H] (CO) C1=CC=CC=C1) =O) C2=CC=C (C=C2) C=3C=CN=CC3
Molecular Formula
C20H19N3O2
Molecular Weight
333.38
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

AS-1892802
CAS Number928320-12-1
PubChem CID46911016
IUPAC Name1-[(1S)-2-hydroxy-1-phenylethyl]-3-(4-pyridin-4-ylphenyl)urea
Molecular FormulaC20H19N3O2
Molecular Weight333.4
XLogP2.3
Topological Polar Surface Area74.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Heavy Atom Count25
Formal Charge0
Complexity398
SMILES
C1=CC=C(C=C1)[C@@H](CO)NC(=O)NC2=CC=C(C=C2)C3=CC=NC=C3
InChI
InChI=1S/C20H19N3O2/c24-14-19(17-4-2-1-3-5-17)23-20(25)22-18-8-6-15(7-9-18)16-10-12-21-13-11-16/h1-13,19,24H,14H2,(H2,22,23,25)/t19-/m1/s1
InChIKey
WDTFYYZHMRBVHK-LJQANCHMSA-N
Chemical Structure
2D Structure
2D structure of AS-1892802
CAS: 928320-12-1
CID: 46911016
Formula: C20H19N3O2
MW: 333.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight333.4
XLogP32.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass333.147726857
Monoisotopic Mass333.147726857
Topological Polar Surface Area74.3 Ų
Heavy Atom Count25
Formal Charge0
Complexity398
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19219736-01BAY 1892005
GTR19170425-01AG-1557 hydrochloride (189290-58-2 (free base) )

Alternative Products

CatalogName
T22037-01AS 1892802
574568AS-1892802

Popular Products